Nefazodone and Symptoms Suggesting Neurotoxicity: A Case Report

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Letter to the Editor

Sir: We report a case of reversible neurotoxicity possibly induced by an increase in the dose of nefazodone.

Case report. Mr. A, a 43-year-old man with schizoaffective disorder, presented with complaints of paranoid ideation, auditory hallucinations, and suicidal ideation. One week prior to admission, he had discontinued his regularly prescribed medications, which included sertraline, risperidone, diazepam, cyclobenzaprine, and carbamazepine.

J Clin Psychiatry 1996;57(12):595 [letter]