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When Neurotrophic Factors Get on Your Nerves: Therapy for Neurodegenerative Disorders

J Clin Psychiatry 1998;59:277-278
In a previous BRAINSTORMS, we reviewed how neurotrophic factors regulate neuronal survival as well as sprouting of axons to form new synaptic connections. Here we discuss the therapeutic potential for neurotrophic factors in disorders characterized by degeneration of neurons, loss of synapses, or both.