Safety in Overdose of Quetiapine: A Case Report
J Clin Psychiatry 1998;59(8):433-433 [letter]
© Copyright 2016 Physicians Postgraduate Press, Inc.
Sir: Quetiapine (Seroquel) is a new atypical antipsychotic drug belonging to a new chemical class, the dibenzothiazepine derivatives. It is a serotonin and dopamine receptor antagonist, which also has antagonistic activity at α-adrenergic and histamine receptor sites. A MEDLINE review of the literature yielded no prior published reports of quetiapine overdosage. Therefore, we report the case of a patient who intentionally ingested a large quantity of quetiapine.