Neuropharmacology of Obesity: My Receptors Made Me Eat It

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Body weight is regulated by complex interrelationships between central and peripheral factors. Satiety, appetite, and craving are CNS drives, whereas metabolism and energy utilization are peripheral endocrine actions. Recent discoveries are lending important insights into how these central and peripheral components of weight control are mediated by receptors for several key neurotransmitters and hormones.

J Clin Psychiatry 1998;59(9):447-448