Adverse Events of Fluoxetine: Postmarketing Compared With Premarketing Clinical Trials
J Clin Psychiatry 2000;61(11):874 [letter]
© Copyright 2017 Physicians Postgraduate Press, Inc.
Letter to the Editor
Sir: A prevalent perception exists among clinical pharmacologists and clinicians that the burden of adverse events is higher when a drug is utilized in the natural clinical environment than when used in premarketing clinical trials. The postmarketing study by Zajecka et al., which reported on the adverse events of fluoxetine, affords the opportunity to test this perception.