Rationale and Guidelines for the Inpatient Treatment of Acute Psychosis
J Clin Psychiatry 2000;61(suppl 14):27-32
© Copyright 2015 Physicians Postgraduate Press, Inc.
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For patients hospitalized with acute episodes of psychosis, rapid stabilization of intense positive
symptoms, hostility, and agitation is typically a preeminent therapeutic goal. These goals often differ
from those of the nonhospitalized patient with psychosis for whom long-term treatment goals such as
improvement of negative symptoms, cognitive function, compliance, and reduction in side effect burden
may be paramount. Therefore, when selecting an antipsychotic treatment for hospitalized patients,
efficacy against positive symptoms and hostility as well as speed of therapeutic onset should
strongly be considered. At the same time, selection of antipsychotic treatment in the inpatient setting
should establish a definitive treatment that will address long-term goals effectively after discharge.
This article presents the rationale and practical guidelines for selection of treatment regimens for patients
hospitalized due to acute psychosis.