Auditory Hallucinations Associated With Topiramate

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Letter to the Editor

Sir: The traditional antiepileptic drugs, such as carbamazepine and valproic acid, may precipitate psychosis in patients being treated for seizures. The efficacy of these agents in the management of bipolar disorder is well established. Recently, a new class of antiepileptic drugs has been used for the treatment of both seizures and bipolar disorder. However, there have been reports of psychosis among epileptics caused by the newer antiepileptic drugs, including topiramate. We describe a case of psychosis associated with topiramate in a patient with no history of seizures.

J Clin Psychiatry 2001;62(8):653