Introduction: Weight Gain and Glucose Regulation During Antipsychotic Drug Treatment

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Excessive increases in body weight as a treatment-emergent effect of atypical antipsychotic drugs has become the focal point of clinical and research interest. Weight gain has long been recognized as a potential side effect of treatment with conventional antipsychotic agents. The lack of demonstrable differences among these older compounds with respect to the incidence and degree of increased body weight made the issue largely irrelevant from a drug selection perspective. After all, not much could be done to avoid the problem. The current situation is different.​

J Clin Psychiatry 2001;62(suppl 23):3-4