Alternative Treatments for Depression: Empirical Support and Relevance to Women.[CME]
J Clin Psychiatry 2002;63(7):628-640
© Copyright 2014 Physicians Postgraduate Press, Inc.
Purchase This PDF for $40.00
If you are not a paid subscriber, you may purchase the PDF.
(You'll need the free Adobe Acrobat Reader.)
Receive immediate full-text access to JCP. You can subscribe to JCP online-only ($86) or print + online ($156 individual).
With your subscription, receive a free PDF collection of the NCDEU Festschrift articles. Hurry! This offer ends December 31, 2011.
If you are a paid subscriber to JCP and do not yet have a username and password, activate your subscription now.
As a paid subscriber who has activated your subscription, you have access to the HTML and PDF versions of this item.
Click here to login.
Did you forget your password?
Still can't log in? Contact the Circulation Department at 1-800-489-1001 x4 or send email
Background: This article is a critical
review of the efficacy of selected alternative
treatments for unipolar depression including exercise,
stress management techniques, acupuncture, St.
John's wort, bright light, and sleep deprivation.
Issues related to women across the life span,
including pregnancy and lactation, are
Data Sources: Evidence of efficacy is
based on randomized controlled trials. A distinction
is made between studies that address depressive symptoms and studies that address
depressive disorders. The review emphasizes issues
related to effectiveness, such as treatment
availability, acceptability, safety, and cost and issues
relevant to women.
Data Synthesis: Exercise, stress
reduction methods, bright light exposure, and sleep
deprivation hold greater promise as adjuncts to
conventional treatment than as monotherapies for
major depression. The evidence to date is not
sufficiently compelling to suggest the use of St.
John's wort in favor of or as an alternative to
existing U.S. Food and Drug
Administration-regulated compounds. Initial evidence suggests that
acupuncture might be an effective alternative monotherapy for major depression, single episode.
Conclusion: This review indicates that
some unconventional treatments hold promise as
alternative or complementary treatments for
unipolar depression in women and have the potential
to contribute to its long-term management. Additional research is needed before further
recommendations can be made, and there is an
urgent need to carefully document and report the
frequency of minor and major side effects.