Effect of Mirtazapine VersusFluoxetine on "Sleep Quality."

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Sir: As a psychiatrist in clinical practice, I appreciate the importance of restoring sleep quality in my depressed patients. I therefore read with interest the recent article by Winokur et al.1 comparing the sleep physiology effects of mirtazapine versus fluoxetine. Unfortunately, the authors seemed to demonstrate only that a drug with a sedative side effect causes more drowsiness than a drug without it.

J Clin Psychiatry 2004;65(8):1149-1150