Login  

 

The article you requested is

Possible Increased Efficacy of Low-Dose Clozapine When Combined With Aripiprazole

J Clin Psychiatry 2004;65:1284-1285 [letter]

Because this piece does not have an abstract, we have provided for your benefit the first 3 sentences of the full text.

Sir: Clozapine has been shown to be superior to typical antipsychotics in treatment-refractory schizophrenic patients. However, patients are sometimes unable to tolerate full therapeutic doses of clozapine because of significant adverse central nervous system and gastrointestinal effects at high doses. Aripiprazole is a new antipsychotic with a novel mechanism of action.