Guideline 17: Selecting Antipsychotics for a Patient With a History of Side Effects




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The experts preferred quetiapine for patients with extrapyramidal side effects (EPS), tardive dyskinesia (TD), or hyperprolacinemia. They preferred risperidone for patients with excessive daytime sedation. The experts would avoid conventional antipsychotics and clozapine in patients with a history of central anticholinergic syndrome or significant peripheral anticholinergic syndrome, tachycardia, or drug-induced orthostatic hypotension.​

J Clin Psychiatry 2004;65(suppl 2):41-41