Introduction. Beyond Refractory Obsessions and Anxiety States: Toward Remission
J Clin Psychiatry 2004;65(suppl 14):3-5
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At the Sixth International Obsessive-Compulsive Disorder Conference (IOCDC), held November
13–15, 2003, in Lanzarote, Spain, 2 issues were discussed that are of great importance to future
research on obsessive-compulsive disorder (OCD). The first of these is the possible inclusion of
obsessive-compulsive spectrum disorders (OCSD) in the fifth edition of the Diagnostic and Statistical
Manual of Mental Disorders. OCSD resemble OCD in their clinical symptoms, associated features,
comorbidity, family/genetics, etiology, and neurocircuitry, as well as their selective response to treatment
with serotonin reuptake inhibitors. The second issue is considering remission as the ultimate
goal of treatment for OCD instead of just symptom reduction, as has been suggested in other disorders.
These and other issues should be discussed at future meetings of the IOCDC and influence how
we conceptualize the disorder and design future treatment trials.