Mirtazapine for Alcohol Dependence: A Case Report

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Sir: While alcohol dependence is highly prevalent, pharmacotherapy options for its management remain relatively limited1 or underutilized.2 Mirtazapine is indicated for the symptomatic treatment of depression. We report a case in which mirtazapine aided the treatment of a depressed alcoholic man, speculating that its 5-HT3 antagonism may have contributed to its beneficial effect on his alcoholism.​

J Clin Psychiatry 2005;66(4):540