Monosymptomatic Hypochondriacal Psychosis: Atypical Presentation and Response to Olanzapine

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Sir: Monosymptomatic hypochondriacal psychosis (MHP) is an illness characterized by a single delusion of somatic type that can present at any age from late adolescence onward, equally affecting both sexes and having a poor prognosis without treatment.1 Infestation with parasites, body dysmorphophobia, and halitosis are the most commonly reported somatic delusions.1 Pimozide has been frequently used and reported to be effective in the treatment of MHP, but has the potential for undesirable side effects including tardive dyskinesia and cardiac conduction defects.1​​

J Clin Psychiatry 2005;66(6):800-801