Reply to Applying Parsimony to "An African Patient With Ziprasidone Intolerance"

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Sir: Our letter is the first report of a dramatically increased serum concentration of ziprasidone and the second report of the occurrence of severe side effects with that same medication, both effects occurring despite a demonstrably normal dose of the drug. As it happens, both patients in question had an African ethnic background. The great William of Occam suggested that “entities are not to be multiplied beyond necessity,”1 the principle that has become known as “Occam’s razor.”​

J Clin Psychiatry 2005;66(11):1491-1492