Reply to "Reexamining Paroxetine and Cognitive-Behavioral Therapy in Postpartum Depression and Anxiety

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Sir: We appreciate the response of Ms. McClendon to our article on paroxetine and cognitive-behavioral therapy (CBT) in the treatment of comorbid postpartum depression and anxiety. We agree that our findings are from women with severe comorbid depression and anxiety, as indicated by their Hamilton Rating Scale for Depression and Hamilton Rating Scale for Anxiety scores at baseline, and are therefore representative of only this select population. Due to the relative lack of research on the clinical effectiveness of combined pharmacologic and psychological interventions for postpartum depression and anxiety, the primary aim of the study was to provide readers with preliminary information on this subject taken from a select sample treated at a tertiary hospital outpatient clinic.​

J Clin Psychiatry 2005;66(11):1495