Effects of the Traditional Chinese Herbal Medicine Yi-Gan San for Cholinesterase Inhibitor-Resistant Visual Hallucinations and Neuropsychiatric Symptoms in Patients With Dementia With Lewy Bodies

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Sir: Dementia with Lewy bodies (DLB) is characterized clinically by progressive and fluctuating cognitive decline, visual hallucinations, and parkinsonism.1 Some studies have reported that cholinesterase inhibitors are at least partially beneficial for treating patients with DLB.2–4 However, Shea et al.5 reported that cholinesterase inhibitors occasionally caused deterioration of parkinsonian symptoms in patients with DLB.​

J Clin Psychiatry 2005;66(12):1612-1613