The State of Knowledge of Chronic Depression.

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Dr. Gelenberg: Let’s begin with a discussion of the definition of chronic depression. What is the clinical relevance of the subtypes of depression in the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV)?1

Dr. McCullough: My colleagues and I have reported on 1316 patients with chronic depression.2,3

J Clin Psychiatry 2006;67(2):179-184