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The article you requested is

Academic Highlights: Emerging Therapies for Bipolar Depression. [CME]

J Clin Psychiatry 2006;67(7):1140-1151

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To put the symptoms and illness outcomes of bipolar depression in proper context, David J. Kupfer, M.D., began by reviewing the symptoms of the 4 domains of bipolar disorder: manic mood and behavior, dysphoric mood and behavior, psychotic symptoms, and cognitive symptoms. Bipolar disorder is a chronic psychiatric illness characterized by depression and at least 1 manic or hypomanic episode during the lifetime course of the illness.1 Patients with bipolar disorder can have symptoms in more than one of these domains concurrently.​​