Discussion: Improving Cognitive Function and Functional Outcome in Severe Mental Illness

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Dr. Tamminga: Considering some of the information on varying proportions of cognitive deficits, does every person have all of those deficits or do some patients with schizophrenia have mainly one deficit and some have mainly another? Hill et al. [Hill SK, et al. J Clin Exp Neuropsychol 2002;24:765–780] suggest that some clusters of patients with schizophrenia have predominantly memory or other deficits and others have global impairments or few impairments.

Dr. Green: You can always statistically find people who are below a cutoff on some domains and not others.​

J Clin Psychiatry 2006;67(suppl 9):36-42