Personality Disorder and Cardiovascular Disease: Results From a National Household Survey. [CME]
J Clin Psychiatry 2007;68(1):69-74
© Copyright 2016 Physicians Postgraduate Press, Inc.
Purchase This PDF for $40.00
If you are not a paid subscriber, you may purchase the PDF.
(You'll need the free Adobe Acrobat Reader.)
Receive immediate full-text access to JCP. You can subscribe to JCP online-only ($86) or print + online ($156 individual).
With your subscription, receive a free PDF collection of the NCDEU Festschrift articles. Hurry! This offer ends December 31, 2011.
If you are a paid subscriber to JCP and do not yet have a username and password, activate your subscription now.
As a paid subscriber who has activated your subscription, you have access to the HTML and PDF versions of this item.
Click here to login.
Did you forget your password?
Still can't log in? Contact the Circulation Department at 1-800-489-1001 x4 or send email
Objective: Little is known about the physical health of personality-disordered people. This study investigated associations between personality disorder and cardiovascular disease in a large, nationally representative sample from Great Britain.
Method: A random sample of 8580 adults aged 16 to 74 years, living in England, Wales, and Scotland in 2000 was screened for the presence of personality disorders using the screening questionnaire of the Structured Clinical Interview for DSM-IV Axis II Personality Disorders. Self-reported stroke or ischemic heart disease was ascertained. Age, sex, social class (by occupation), self-reported hypertension or diabetes, smoking history, and alcoholism were entered into regression models as potential confounding/mediating factors.
Results: Participants screening positive for any personality disorder were more likely to report experiencing a stroke and ischemic heart disease (age- and sex-adjusted odds ratios [ORs] were 2.1 [95% CI, 1.2 to 3.8] and 1.5 [95% CI, 1.1 to 2.1], respectively). After adjusting for potential confounders, significant associations were found between any personality disorder and stroke (OR = 1.9; 95% CI, 1.0 to 3.5) and any personality disorder and ischemic heart disease (OR = 1.4; 95% CI, 1.0 to 1.9). After adjustment, avoidant (OR = 4.0; 95% CI, 1.2 to 13.3), obsessive-compulsive (OR = 2.9; 95% CI, 1.3 to 6.6), and borderline personality disorders (OR = 8.5; 95% CI, 1.0 to 72.8) were significantly associated with stroke. Ischemic heart disease was significantly associated with avoidant (OR = 2.2; 95% CI, 1.1 to 4.5), paranoid (OR = 2.1; 95% CI, 1.0 to 4.3), schizotypal (OR = 3.6; 95% CI, 1.5 to 8.6), schizoid (OR = 1.6; 95% CI, 1.1 to 2.4), and borderline personality disorders (OR = 7.2; 95% CI, 2.1 to 24.3).
Conclusion: People at risk for personality disorder are also at increased risk for cardiovascular disease. This increased risk is not explained by differences in socioeconomic status or lifestyle. Dysfunctional personality traits may have a direct role in the etiology of cardiovascular disease.