Decreased Lipoprotein Lipase as a Risk Factor for Atypical Neuroleptic-Induced Hypertriglyceridemia
Kenji Yamamoto, MD, PhD; Masamichi Fukuda, MD; Akiko Nogawa, MD; Eri Takahashi, MD, PhD; Hitoshi Miyaoka, MD, PhD
Because this piece does not have an abstract, we have provided for your benefit the first 3 sentences of the full text.
Sir: Neuroleptics often increase appetite. This increased appetite can lead to severe hypertriglyceridemia in patients with uncommon congenital lipoprotein lipase (LPL) deficiency. During neuroleptic therapy, attention should be paid to the potential for severe hypertriglyceridemia (> 1000 mg/dL) that increases the risk of atherosclerosis and can cause fatal acute pancreatitis.1,2
J Clin Psychiatry 2007;68(5):802-802
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