Applicability of the Oral Glucose Tolerance Test in Assessing Prevalence and Incidence of Diabetes Mellitus in Schizophrenia

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Sir: In their very interesting article “Screening for Diabetes and Other Metabolic Abnormalities in Patients With Schizophrenia and Schizoaffective Disorder: Evaluation of Incidence and Screening Methods,”1 van Winkel et al. report on use of an oral glucose tolerance test (OGTT) in 415 mainly inpatients (73.7%) in a Belgian psychiatric hospital. The numbers involved convincingly show that OGTT is a feasible option in the diagnosis of (pre)diabetes in schizophrenia.

The study, nevertheless, raises some methodological questions.​

J Clin Psychiatry 2007;68(8):1307-1308