The article you requested is

Gender Imbalance in Clinical Trials in Schizophrenia

J Clin Psychiatry 2008;69(3):498-499 [letter]

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Sir: A recent study on the prevalence of schizophrenia in the general population using a structured clinical interview evidenced no sex difference in lifetime prevalence: 0.82% (95% CI = 0.56 to 1.19) for men and 0.91% (0.65 to 1.27) for women.1 These figures are in agreement with a review of 1721 prevalence estimates of schizophrenia from 188 epidemiologically heterogeneous studies (published between 1965 and 2002) showing no significant differences between genders.2 Our own records from Puente de Vallecas Health Center in Madrid, Spain, which is the referral mental health center for approximately 250,000 inhabitants, showed a male/female ratio of 1.33 among the 1104 patients who received a diagnosis of schizophrenia (based on ICD-9 criteria) between 1990 and 2005.​