Increased Rate of Non-Right-Handedness in Patients With Bipolar Disorder

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Letter to the Editor

Sir: Non–right-handedness is more prevalent in subjects with mental disorders (up to 28%) compared to the general population (8%–10%). Data on the association of non–righthandedness to bipolar disorder specifically are ambiguous, with data suggesting increased, similar, and decreased rates of non–right-handedness in those with bipolar disorder compared to the general population. Putative differences in handedness could yield insights into lateralized cerebral organization or dysfunction as a contributor to pathology in bipolar disorders.

J Clin Psychiatry 2008;69(5):866-867