Treating Movement Disorders and Akathisia as Side Effects of Antipsychotic Pharmacotherapy




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One of the most common reasons for switching antipsychotic medication is to reduce the burden of side effects, particularly movement disorders and akathisia associated with typical antipsychotics. Adjusting the antipsychotic dose and, if necessary, switching treatment to an antipsychotic with a low extrapyramidal symptom liability may help to optimize the clinical management of schizophrenia. Switching from a typical to an atypical antipsychotic or between atypical antipsychotics involves considering a variety of factors relating to the patient, illness, medication, and the patient’s environment.​

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J Clin Psychiatry 2008;69(5):e14