Is Aripiprazole an Efficacious Adjunct for Unipolar Depression?

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Letter to the Editor

Sir: As part of a psychiatry residents’ journal club, we reviewed the recently published study by Berman et al. on the efficacy of adjunctive aripiprazole versus adjunctive placebo in patients with unipolar, nonpsychotic major depression. We identified one potential confounding factor, for which we thought further data might provide some clarification.

J Clin Psychiatry 2008;69(6):1021