Folate Supplementation: Is It Safe and Effective?
J Clin Psychiatry 2009;70(5):767 [letter]
© Copyright 2015 Physicians Postgraduate Press, Inc.
Purchase This PDF for $40.00
If you are not a paid subscriber, you may purchase the PDF.
(You'll need the free Adobe Acrobat Reader.)
Receive immediate full-text access to JCP. You can subscribe to JCP online-only ($86) or print + online ($156 individual).
With your subscription, receive a free PDF collection of the NCDEU Festschrift articles. Hurry! This offer ends December 31, 2011.
If you are a paid subscriber to JCP and do not yet have a username and password, activate your subscription now.
As a paid subscriber who has activated your subscription, you have access to the HTML and PDF versions of this item.
Click here to login.
Did you forget your password?
Still can't log in? Contact the Circulation Department at 1-800-489-1001 x4 or send email
Letter to the Editor
Sir: In the September 2008 issue of the Journal, Stahl reviews
L-methylfolate as a possibly helpful adjunctive antidepressant
agent,1 and Mischoulon and Fava briefly review the
evidence that folates, including folic acid, a stable synthetic
substance, could be useful augmenting antidepressant agents.
However, there is some evidence of possibly harmful or, at the
least, disappointing effects of folate supplementation.
- There has long been a concern that folate supplementation
might mask, or even worsen, the manifestations
of B12-deficiency anemia. L-Methylfolate may be less
likely to do this than folic acid.