Reply to Folate Supplementation: Is It Safe and Effective?

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Letter to the Editor

Sir: We appreciate Dr. Frankenburg’s thoughtful letter outlining her reservations about the proposed use of folate supplementation in the psychiatric field. Dr. Frankenburg points out a number of concerns regarding potentially harmful effects of folate. We have considered these issues and conducted some additional literature review to address her questions.

J Clin Psychiatry 2009;70(5):767-769