Reply to Keeping ’Em Honest: The Current Crisis of Confidence in Antidepressants
J Clin Psychiatry 2011;72(7):1015-1016 [letter]
© Copyright 2014 Physicians Postgraduate Press, Inc.
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Letter to the Editor
Because this piece does not have an abstract, we have provided for your benefit the first 3 sentences of the full text.
We appreciate Dr Teboul’s careful reading of the publication that arose from our roundtable conference. His comments about the magnitude of a difference between active treatments using the NICE guidelines are reasonable up until he critiques the meta-analysis of mirtazapine and SSRIs. Here, he focuses on the slight remission rate difference in favor of mirtazapine (NNT = 23) and claims that we were misleading readers by failing to interpret “minor differences as anything more than clinically negligible.”