Discussion: A Fresh Look at Monoamine Oxidase Inhibitors for Depression
J Clin Psychiatry 2012;73(suppl 1):42-45
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Dr Sclar: What is the difference between treatment resistance and treatment failure?
Dr Thase: Treatment failure is a broader term that incorporates several factors, such as poor tolerability, treatment nonadherence, or simply treatment nonresponse. The term also implies a failure of the doctor-patient relationship, meaning that the physician was unable to engage the patient in a productive alliance.