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ASCP Corner: Decision Making and Antipsychotic Medication Treatment for Youth With Autism Spectrum Disorders: Applying Guidelines in the Real World

J Clin Psychiatry 2013;74(10):1022-1024
10.4088/JCP.13ac08691
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Autism spectrum disorder (ASD) is a diagnosis that is characterized by varying degrees of (1) impairment in social reciprocity, (2) impairment in social communication,and (3) repetitive, restrictive, stereotyped patterns of interests, activities, and behaviors. While ASD prevalence varies across regions, recent prevalence rates range from 1:88 children in the United States to 1:160 children worldwide.

Currently, only 2 atypical antipsychotics, risperidone (in 5- to 16-year-olds) and aripiprazole (in 6- to 17-year-olds),are approved by the US Food and Drug Administration (FDA) for treatment of significant irritability (aggression toward others, deliberate self-injuriousness, temper tantrums, and labile moods) associated with ASD.