Introduction. Antipsychotic Standard of Care: Redefining the Definition of Atypical Antipsychotics

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Antipsychotic medications (neuroleptics) have been the mainstay of treating acute and chronic psychoses for the past several decades. While they have clearly advanced the treatment of psychoses, there have been limitations in efficacy and substantial adverse effects from their use. Neuroleptics are more effective against positive than negative symptoms, and adverse effects often lead to discontinuation and relapses.​

J Clin Psychiatry 2000;61(suppl 3):3-3