Sertraline Versus Venlafaxine XR in Major Depressive Disorder

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Sir: A recent study by Shelton et al.1 suggests that sertraline and venlafaxine XR have a comparable efficacy in treating major depressive disorder. The following comments would enable an improved understanding of this study. Shelton et al.1 stated that participants were outpatients but did not clarify what process was involved in such recruitment.​

J Clin Psychiatry 2007;68(10):1618-1619