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3  Guest Editor's Introduction: Diagnosis and Treatment of Insomniaat the Start of the 21st Century.

Constantin R. Soldatos

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8  The Extent and Impact of Insomniaas a Public Health Problem

Christer G. M. Hublin

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13  Insomnia and the 2-Process Model of Sleep Regulation:Etiopathogenic Considerations

Domien G. M. Beersma

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17  Psychological and Psychiatric Issuesin the Etiopathogenesis of Insomnia

Peter J. Hauri

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21  Contributions of Cognitive-Behavioral Approachesto the Clinical Management of Insomnia

Charles M. Morin

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27  The Pharmacotherapy of Insomnia: Efficacy and Rebound With Hypnotic Drugs.

Dimitris G. Dikeos and Constantin R. Soldatos

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33  Managing Dependence and Withdrawal With Newer Hypnotic Medications in the Treatment of Insomnia.

Malcolm H. Lader

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38  Residual Effects on Memory and Psychomotor Performance of Zaleplon and Other Hypnotic Drugs.

James F. O’Hanlon

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45  A Breakthrough in the Pharmacologic Management of Insomnia: Overview of the Clinical Profile of Zaleplon.

Raymond Cluydts

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