Methylphenidate-Induced Akathisia in a Patient With Multiple Sclerosis

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Sir: Methylphenidate is a short-acting psychostimulant that is structurally and pharmacologically similar to dextroamphetamine and is primarily used in the treatment of attention-deficit/ hyperactivity disorder (ADHD).1,2 Its use has also been explored for the treatment of apathy and for augmentation of effects of antidepressants.3 It acts as a dopaminergic and noradrenergic reuptake inhibitor.​

Prim Care Companion J Clin Psychiatry 2006;8(6):379-380 [letter]