Psychiatric Briefs

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Background: Preliminary reports suggest that menstrual cycle irregularities occur more commonly in women with bipolar disorder and unipolar depression than in the general population. However, it is not always clear whether such abnormalities, reflecting disruption of the hypothalamic-pituitary-gonadal axis, are caused by psychotropic treatments or associated with the disorder per se.​

Prim Care Companion J Clin Psychiatry 2006;8(6):384-387