Vitamin B12 Deficiency Manifested as Mania: A Case Report

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Sir: Multiple psychiatric symptoms may precede pernicious anemia. Only 1 case of full manic syndrome secondary to B12 deficiency has been reported.1 

Case report. Ms. A was a 35-year-old woman with no personal or family history of psychiatric disorders, who was admitted to the hospital in February of 2005 with a 3-week history of episodes of manic symptoms of several hours’ duration, including grandiosity, hyperactivity, sexual indiscretion, hyperphagia, irritable mood, reckless behavior, flight of ideas, and overbearing manner.

Prim Care Companion J Clin Psychiatry 2007;9(3):238 [letter]