Quetiapine-Induced Bradycardia Without QT Interval Prolongation in an Elderly Woman

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To the Editor: Bradycardia has recently been reported as a rare but severe adverse effect of atypical antipsychotics like risperidone,1,2 olanzapine,3 and clozapine.4 Most case reports describe bradycardia with QT interval prolongation. 1–5 Until now, the mechanism of this bradyarrhythmogenic character of atypical antipsychotics has not fully been understood.​

Prim Care Companion J Clin Psychiatry 2009;11(4):172-173[letter]