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Difficulties in Diagnosis and Management of Bipolar Disorder: Three Case Presentations

Kathleen T. Brady, M.D., Ph.D.

Bipolar disorder is associated with significant problems in patient management, including misdiagnosis, noncompliance, and comorbid substance use disorders. This article describes strategies for the management of difficult cases, with particular emphasis on the choice of therapeutic agents, such as mood stabilizers and atypical antipsychotics, for optimal control of symptoms and psychosocial interventions for reinforcement of therapeutic interventions. Special attention is given to the relationship between bipolar disorder and substance use disorders.

(J Clin Psychiatry 2000;61[suppl 13]:32–37)

From the Medical University of South Carolina, Charleston.

Presented at the Bipolar Disorder Advisory Summit, which was held August 13–15, 1999, in New York, N.Y., and supported by Janssen Pharmaceutica, L.P.

Reprint requests to: Kathleen T. Brady, M.D., Ph.D., Department of Psychiatry, Medical University of South Carolina, 67 President St., P.O. Box 250861, Charleston, SC 29425 (e-mail: bradyk@musc.edu).