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Brainstorms

Apoptosis: Neuronal Death by Design

Excitotoxicity and Neuroprotection

Mental Illness May Be Damaging to Your Brain

"Awakening" From Schizophrenia: Intramolecular Polypharmacy and the Atypical Antipsychotics

Estrogen Makes the Brain a Sex Organ

Sex Therapy in Psychiatric Treatment Has a New Partner: Reproductive Hormones

Serotonin: It's Possible to Have Too Much of a Good Thing

How Psychiatrists Can Build New Therapies for Impotence

Nitric Oxide Physiology and Pharmacology

Brain Tonics for Brain Sprouts: How Neurotrophic Factors Fertilize Neurons

Recognition Molecules Are Trailblazers for Axon Pathways

What Makes an Antipsychotic Atypical?

Neuropharmacology of Obesity: My Receptors Made Me Eat It

How to Appease the Appetite of Psychotropic Drugs

Getting Stoned Without Inhaling: Anandamide Is the Brain's Natural Marijuana

Brainstorms: Using Secondary Binding Properties to Select a Not So Selective Serotonin Reuptake Inhibitor

Peptides and Psychiatry, Part 1: How Synthesis of Neuropeptides Differs From Classical Neurotransmitter Synthesis

Peptides and Psychiatry, Part 3: Substance P and Serendipity: Novel Psychotropics Are a Possibility

Why Settle for Silver, When You Can Go for Gold? Response vs. Recovery as the Goal of Antidepressant Therapy.

Mergers and Acquisitions Among Psychotropics: Antidepressant Takeover of Anxiety May Now Be Complete

Antidepressants: The Blue-Chip Psychotropic for the Modern Treatment of Anxiety Disorders

Antipsychotic Polypharmacy, Part 1: Therapeutic Option or Dirty Little Secret?

Antipsychotic Polypharmacy, Part 2: Tips on Use and Misuse

Molecular Neurobiology for Practicing Psychiatrists, Part 5: How a Leucine Zipper Can Turn On Genes: Immediate-Early Genes Activate Late-Gene Expression in the Brain

Blue Genes and the Monoamine Hypothesis of Depression

Blue Genes and the Mechanism of Action of Antidepressants

The 7 Habits of Highly Effective Psychopharmacologists: Overview

The 7 Habits of Highly Effective Psychopharmacologists, Part 2: Begin With the End in Mind

The 7 Habits of Highly Effective Psychopharmacologists, Part 3: Sharpen the Saw With Selective Choices of Continuing Medical Education Programs

The 7 Habits of Highly Effective Psychopharmacologists, Part 4: Developing and Implementing the Vision

Paying Attention to Your Acetylcholine, Part 2: The Function of Nicotinic Receptors

The New Cholinesterase Inhibitors for Alzheimer's Disease, Part 1: Their Similarities Are Different

The New Cholinesterase Inhibitors for Alzheimer's Disease, Part 2: Illustrating Their Mechanisms of Action

New Drug Discovery in the Postgenomic Era: From Genomics to Proteomics

Does Evidence From Clinical Trials in Psychopharmacology Apply in Clinical Practice?

The Psychopharmacology of Sex, Part 1: Neurotransmitters and the 3 Phases of the Human Sexual Response

The Psychopharmacology of Sex, Part 2: Effects of Drugs and Disease on the 3 Phases of Human Sexual Response

Brainstorms: Why Drugs and Hormones May Interact in Psychiatric Disorders

Effects of Estrogen on the Central Nervous System.

Natural Estrogen as an Antidepressant for Women

Brainstorms: Fibromyalgia: The Enigma and the Stigma.

Gut Feelings About Irritable Bowel Syndrome

"Hit-and-Run" Actions at Dopamine Receptors, Part 1: Mechanism of Action of Atypical Antipsychotics

"Hit-and-Run" Actions at Dopamine Receptors, Part 2: Illustrating Fast Dissociation From Dopamine Receptors That Typifies Atypical Antipsychotics

Dopamine System Stabilizers, Aripiprazole, and the Next Generation of Antipsychotics, Part 1: "Goldilocks" Actions at Dopamine Receptors

Brainstorms: Dopamine System Stabilizers, Aripiprazole, and the Next Generation of Antipsychotics, Part 2: Illustrating Their Mechanism of Action

Antipsychotic Polypharmacy: Squandering Precious Resources?

Selective Actions on Sleep or Anxiety by Exploiting GABA-A/Benzodiazepine Receptor Subtypes

The Psychopharmacology of Painful Physical Symptoms in Depression

Awakening to the Psychopharmacology of Sleep and Arousal: Novel Neurotransmitters and Wake-Promoting Drugs

Brainstorms--5 Years and Counting

Psychopharmacology of Wakefulness: Pathways and Neurotransmitters

Don't Ask, Don't Tell, but Benzodiazepines Are Still the Leading Treatments for Anxiety Disorder

Independent Actions on Fear Circuits May Lead to Therapeutic Synergy for Anxiety When Combining Serotonergic and GABAergic Agents

Can Psychopharmacologic Treatments That Relieve Symptoms Also Prevent Disease Progression?

Brainstorms: "The Metabolic Syndrome": Psychopharmacologists Should Weigh the Evidence for Weighing the Patient

Brainstorms: Neurotransmission of Cognition, Part 2 Selective NRIs Are Smart Drugs: Exploiting Regionally Selective Actions on Both Dopamine and Norepinephrine to Enhance Cognition

Brainstorms: Neurotransmission of Cognition, Part 3. Mechanism of Action of Selective NRIs: Both Dopamine and Norepinephrine Increase in Prefrontal Cortex

Brainstorms: Symptoms and Circuits, Part 1: Major Depressive Disorder

Brainstorms: Symptoms and Circuits, Part 3: Schizophrenia

Brainstorms: Anticonvulsants as Anxiolytics, Part 1: Tiagabine and Other Anticonvulsants With Actions on GABA

Brainstorms: Anticonvulsants as Anxiolytics, Part 2: Pregabalin and Gabapentin as α<sub>2</sub>δ Ligands at Voltage-Gated Calcium Channels

Brainstorms: Anticonvulsants and the Relief of Chronic Pain: Pregabalin and Gabapentin as α<sub>2</sub>δ Ligands at Voltage-Gated Calcium Channels

Brainstorms: Anticonvulsants as Mood Stabilizers and Adjuncts to Antipsychotics: Valproate, Lamotrigine, Carbamazepine, Oxcarbazepine and Actions at Voltage-Gated Sodium Channels

Brainstorms: Mechanism of Action of Voltage Sensitive Sodium Channel Modulators

Brainstorms: Mechanism of Action of α<sub>2</sub>δ Ligands: Voltage Sensitive Calcium Channel (VSCC) Modulators

Brainstorms: Psychopharmacology of Anticonvulsants: Levetiracetam as a Synaptic Vesicle Protein Modulator

Brainstorms: Drug Combinations for Bipolar Spectrum Disorders: Evidence-Based Prescribing or Prescribing-Based Evidence?

Brainstorms: Prophylactic Antipsychotics: Do They Keep You From Catching Schizophrenia?

Brainstorms: Preemptive Analgesia: Is Pain Less Costly When You Pre-Pay For It?

Brainstorms: Is Psychopharmacologic "Inoculation" Effective in Preventing Posttraumatic Stress Disorder?

Brainstorms: L-Methylfolate: A Vitamin for Your Monoamines

Brainstorms: The Sigma Enigma: Can Sigma Receptors Provide a Novel Target for Disorders of Mood and Cognition?

Brainstorms: Vasomotor Symptoms and Depression in Women, Part 1. Role of Vasomotor Symptoms in Signaling the Onset or Relapse of a Major Depressive Episode

Brainstorms: Vasomotor Symptoms and Depression in Women, Part 2. Treatments That Cause Remission and Prevent Relapses of Major Depressive Episodes Overlap With Treatments for Vasomotor Symptoms

BRAINSTORMS: Norepinephrine and Dopamine Regulate Signals and Noise in the Prefrontal Cortex

Brainstorms: The Prefrontal Cortex Is Out of Tune in Attention-Deficit/Hyperactivity Disorder

Brainstorms: Epigenetics and Methylomics in Psychiatry

Brainstorms: Combining Antidepressant Therapies From the Initiation of Treatment: A Paradigm Shift for Major Depression

Brainstorms: Mechanism of Action of Stimulants in Attention-Deficit/Hyperactivity Disorder

Mechanism of Action of α<sub>2A</sub>-Adrenergic Agonists in Attention-Deficit/Hyperactivity Disorder With or Without Oppositional Symptoms

Circuits of Sexual Desire in Hypoactive Sexual Desire Disorder

Targeting Circuits of Sexual Desire as a Treatment Strategy for Hypoactive Sexual Desire Disorder

Illustrating the Circuits of Sexual Desire

The Serotonin-7 Receptor as a Novel Therapeutic Target