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Measure of Anxiety in MDD
Mark Zimmerman, MD

Anxiety is high in patients with MDD. Learn about a reliable self-administered scale that measures both anxiety and depression.

» Read this post

» Read the entire blog

Understanding the Lifetime Course of Schizophrenia Rimal B. Bera, MD, et al

Read about the biology of schizophrenia, the longitudinal course of cognitive impairment, social cognition as an emerging area of research, and other related topics.

>>See the entire activity

Treatment of Bipolar Depression Terence A. Ketter, MD

Review the current therapies for bipolar disorder and learn about new treatment strategies that may be beneficial for your patients with bipolar depression.

>>See the entire activity

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Articles published electronically 7/22/14

Efficacy and Safety of Adjunctive Armodafinil in Adults With Major Depressive Episodes Associated With Bipolar I Disorder: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial

[Abstract] [Full Text] Posted 7/22/14

Dose Reduction of Risperidone and Olanzapine and Estimated Dopamine D2 Receptor Occupancy in Stable Patients With Schizophrenia: Findings From an Open-Label, Randomized, Controlled Study

[Abstract] [Full Text] Posted 7/22/14

Articles published electronically 7/8/14

Appetite Regulatory Hormones in Women With Anorexia Nervosa: Binge-Eating/Purging Versus Restricting Type

[Abstract] [Full Text] Posted 7/8/14

Depressed Parents’ Attachment: Effects on Offspring Suicidal Behavior in a Longitudinal Family Study

[Abstract] [Full Text] Posted 7/8/14

Recombinant Human Erythropoietin to Target Cognitive Dysfunction in Bipolar Disorder: A Double-Blind, Randomized, Placebo-Controlled Phase 2 Trial

[Abstract] [Full Text] Posted 7/8/14

Surfing for Suicide Methods and Help: Content Analysis of Websites Retrieved With Search Engines in Austria and the United States

[Abstract] [Full Text] Posted 7/8/14

Cognitive Effects of Pharmacotherapy for Major Depressive Disorder: A Systematic Review

[Abstract] [Full Text] Posted 7/8/14

Articles published electronically 6/24/14

The Relationship Between Adverse Childhood Experiences and Symptom Severity, Chronicity, and Comorbidity in Patients With Obsessive-Compulsive Disorder

[Abstract] [Full Text] Posted 6/24/14

Efficacy and Safety of Quetiapine-XR as Monotherapy or Adjunctive Therapy to a Mood Stabilizer in Acute Bipolar Depression With Generalized Anxiety Disorder and Other Comorbidities: A Randomized, Placebo-Controlled Trial

[Abstract] [Full Text] Posted 6/24/14

Articles published electronically 6/10/14

The Role of Patient Expectancy in Placebo and Nocebo Effects in Antidepressant Trials

[Abstract] [Full Text] Posted 6/10/14

Interactions of Borderline Personality Disorder and Mood Disorders Over 10 Years

[Abstract] [Full Text] Posted 6/10/14

Articles published electronically 5/13/14

Two-Year Course Trajectories of Anxiety Disorders: Do DSM Classifications Matter?

[Abstract] [Full Text] Posted 5/13/14

Treatment of Major Depressive Disorder Using Botulinum Toxin A: A 24-Week Randomized, Double-Blind, Placebo-Controlled Study

[Abstract] [Full Text] Posted 5/13/14

Articles published electronically 4/15/14

Effect of Adjunctive l-Methylfolate 15 mg Among Inadequate Responders to SSRIs in Depressed Patients Who Were Stratified by Biomarker Levels and Genotype: Results From a Randomized Clinical Trial

[Abstract] [Full Text] Posted 4/15/14

Articles published electronically 3/31/14

Physical Activity Interventions for People With Mental Illness: A Systematic Review and Meta-Analysis

[Abstract] [Full Text] [Related Blog Post FREE to registered users] Posted 3/31/14

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Volume 75July 2014Number 7

Publisher’s Note

716 The CNS Job Market: A New Service for Our Readers [Free Access]

Original Research

720 Risk of Suicidal Behavior With Antidepressants in Bipolar and Unipolar Disorders

731 Effects of Antidepressants on Longevity and Dementia Onset Among Adults With Down Syndrome: A Retrospective Study

738 Prognostic Subgroups for Citalopram Response in the STAR*D Trial

765 Varenicline for Smoking Cessation in Bipolar Disorder: A Randomized, Double-Blind, Placebo-Controlled Study

Case Series

728 False-Positive Phencyclidine Drug Screenings During Psychopharmacologic Treatment


773 Efficacy of Varenicline for Smoking Cessation in Bipolar Disorder

ASCP Corner

775 Whatever Happened to New Treatments for Alzheimer’s Disease?

Focus on Addiction

748 Focus on Addiction: Buspirone for Cocaine Relapse and Monitoring Controlled Substances Prescribed to Dually Diagnosed Patients

750 Prescription Drug Monitoring Program Inquiry in Psychiatric Assessment: Detection of High Rates of Opioid Prescribing to a Dual Diagnosis Population [CME] [Free Access]

757 Multisite, Randomized, Double-Blind, Placebo-Controlled Pilot Clinical Trial to Evaluate the Efficacy of Buspirone as a Relapse-Prevention Treatment for Cocaine Dependence

Letters to the Editor

777 Brief Pulse and Ultrabrief Pulse Right Unilateral Electroconvulsive Therapy (ECT) for Major Depression: Efficacy, Effectiveness, and Cognitive Effects

778 Doubting the Efficacy/Effectiveness of Electroencephalographic Neurofeedback in Treating Children With Attention-Deficit/Hyperactivity Disorder Is As Yet Unjustified

Online Exclusives

Original Research

e666 Predictors of the Impact of Nonpharmacologic Interventions for Agitation in Nursing Home Residents With Advanced Dementia

e672 Long-Term, Low-Dose Lithium Treatment Does Not Impair Renal Function in the Elderly: A 2-Year Randomized, Placebo-Controlled Trial Followed by Single-Blind Extension

Review Article

e679 Mood Disorders in Restless Legs Syndrome (Willis-Ekbom Disease) [Free Access]


e695 A Meta-Analysis of Computerized Cognitive-Behavioral Therapy for the Treatment of DSM-5 Anxiety Disorders

Case Report

e705 Massive, Previously Undetected Cancer Metastasis Revealed by Application of a Depot Antipsychotic: A Case Report

Practical Psychopharmacology

e707 Nonsteroidal Anti-inflammatory Drugs and 5-HT3 Serotonin Receptor Antagonists as Innovative Antipsychotic Augmentation Treatments for Schizophrenia

Book Reviews

e710 Professionalism in Psychiatry

e711 Borderline Personality Disorder: An Evidence-Based Guide for Generalist Mental Health Professionals

e712 Positive Psychology at the Movies: Using Films to Build Character Strengths and Well-Being, 2nd ed

Online Activities

e17 Emerging Trends: Novel Molecular Targets and Moving Beyond Acute Symptoms in Bipolar Depression [CME]

e18 The Glutamate Hypothesis of Schizophrenia [CME]

e19 Current Standards of Treatment in MS and the Role of Oral Agents [CME]

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The Journal of Clinical Psychiatry is the official journal of the American Society for Clinical Psychopharmacology

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Nonsteroidal Anti-inflammatory Drugs and 5-HT3 Serotonin Receptor Antagonists as Innovative Antipsychotic Augmentation Treatments for Schizophrenia
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A Primer for the Conceptualization of the Mechanism of Action of Electroconvulsive Therapy, 2: Organizing the Information
[Full Text With Comments]

A Primer for the Conceptualization of the Mechanism of Action of Electroconvulsive Therapy, 1: Defining the Question Chittaranjan Andrade
[Full Text With Comments]

Potentially Significant Versus Clinically Significant Drug Interactions: Pomegranate Juice as a Case in Point Chittaranjan Andrade
[Full Text With Comments]

Antidepressants and Testicular Cancer: Cause Versus Association Chittaranjan Andrade
[Full Text With Comments]

Selective Serotonin Reuptake Inhibitor Drug Interactions in Patients Receiving Statins Chittaranjan Andrade
[Full Text With Comments]

Augmenting Selective Serotonin Reuptake Inhibitors With Clomipramine in Obsessive-Compulsive Disorder: Benefits and Risks Chittaranjan Andrade
[Full Text With Comments]

Learning From History: How to Swallow a Pill Chittaranjan Andrade
[Full Text With Comments]

Famotidine Augmentation in Schizophrenia: Hope or Hype? Chittaranjan Andrade
[Full Text With Comments]

Levothyroxine in Psychiatry: Issues Related to Absorption After Oral Dosing Chittaranjan Andrade
[Full Text With Comments]

Antenatal Exposure to Selective Serotonin Reuptake Inhibitors and Duration of Gestation Chittaranjan Andrade
[Full Text With Comments]

Low-Dose Amisulpride and Elevation in Serum Prolactin Chittaranjan Andrade
[Full Text With Comments]

Signal-to-Noise Ratio, Variability, and Their Relevance in Clinical Trials Chittaranjan Andrade
[Full Text With Comments]

Lessons Learned From d-Cycloserine: The Promise and Limits of Drug Facilitation of Exposure Therapy Thomas L. Rodebaugh and Eric J. Lenze
[Full Text With Comments]

Antidepressant Action of Atypical Antipsychotics: Focus on Ziprasidone Monotherapy, With a Few Twists in the Tale Chittaranjan Andrade
[Full Text With Comments]

Augmentation of Venlafaxine With Bupropion: Risks Associated With a Triple Monoamine Reuptake Inhibition Approach to Partially Responsive Depression Chittaranjan Andrade
[Full Text With Comments]

Drug Interactions in the Treatment of Depression in Patients Receiving β-Blocker Drugs Chittaranjan Andrade
[Full Text With Comments]

Drug Interactions in the Treatment of Depression in Patients With Ischemic Heart Disease Chittaranjan Andrade
[Full Text With Comments]

Serotonin Reuptake Inhibitor Treatment of Obsessive-Compulsive Symptoms in Clozapine-Medicated Schizophrenia Chittaranjan Andrade
[Full Text With Comments]

There’s More to Placebo-Related Improvement Than the Placebo Effect Alone Chittaranjan Andrade
[Full Text With Comments]

Breast Cancer and Antidepressant Use Chittaranjan Andrade
[Full Text With Comments]

Modafinil and Armodafinil in Schizophrenia Chittaranjan Andrade
[Full Text With Comments]

Drugs That Escape Hepatic Metabolism Chittaranjan Andrade
[Full Text With Comments]

Practical Psychopharmacology: Schizophrenia and Smoking Chittaranjan Andrade
[Full Text With Comments]

Practical Psychopharmacology: Selective Serotonin Reuptake Inhibitors and Persistent Pulmonary Hypertension of the Newborn Chittaranjan Andrade
[Full Text With Comments]

Commentary: Depression in Women: Windows of Vulnerability and New Insights Into the Link Between Estrogen and Serotonin Sonali Lokuge, Benicio N. Frey, Jane A. Foster, Claudio N. Soares, and Meir Steiner
[Full Text With Comments]

Does DSM-IV Already Capture the Dimensional Nature of Personality Disorders? Mark Zimmerman, Iwona Chelminski, Diane Young, Kristy Dalrymple and Jennifer Martinez
[Full Text With Comments]

A National Epidemic of Unintentional Prescription Opioid Overdose Deaths: How Physicians Can Help Control It Leonard J. Paulozzi, Richard H. Weisler, and Ashwin A. Patkar
[Full Text With Comments]

Editors’ Perspectives: Peer Review and the Evolving Journal

Commentaries on Peer Review and the Evolving Journal. Marlene P. Freeman
[Full Text With Forum]

Peer Review Perspective for Early Career Psychiatrists. Alan J. Gelenberg
[Full Text With Forum]

Learning to Review. Robert Freedman
[Full Text With Forum]

Peer Review by Early Career Psychiatrists: An Opportunity for Development. Anne F. Gross, Ilse R. Wiechers, and Theodore A. Stern
[Full Text With Forum]

The Evolution of the Psychiatry Research Journal. John H. Krystal
[Full Text With Forum]

Peer Review in Early Career: Just Say Yes! Peter P. Roy-Byrne
[Full Text With Forum]

Perspectives on Perinatal Depression Treatment

Perinatal Psychiatry: The Challenges of Making Rational Treatment Decisions at the Interface of Psychiatry and Obstetrics. Marlene P. Freeman
[Full Text With Forum]

Influence of the Media on Women Taking Antidepressants During Pregnancy. Adrienne Einarson
[Full Text With Forum]

The Other Side of the Risk Equation: Exploring Risks of Untreated Depression and Anxiety in Pregnancy. Ellen M. Markus and Laura J. Miller
[Full Text With Forum]

Reflections on Perinatal Depression Treatment. Bryanne Barnett, and Marie-Paule Austin
[Full Text With Forum]

Do We Scare Because We Care? Diane N. Solomon
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Perinatal Depression: Searching for Specific Tools for a Closer Look at This Window. Claudio N. Soares, and Meir Steiner
[Full Text With Forum]

Psychotherapeutic Treatment Options for Perinatal Depression: Emphasis on Maternal-Infant Dyadic Outcomes. Maria Muzik, Sheila M. Marcus, and Heather A. Flynn
[Full Text With Forum]

No Decision Is Without Risk. Rita Suri, and Lori L. Altshuler
[Full Text With Forum]

The Cost of Restricting Knowledge. Anna R. Brandon, Geetha Shivakumar, Stephen J. Inrig, Simon J. Craddock Lee, and John Z. Sadler
[Full Text With Forum]

Pharmacotherapy or Untreated Antenatal Depression: A False Dichotomy. Sona Dimidjian, and Michael W. O’Hara
[Full Text With Forum]


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Switching Antipsychotic Medications to Reduce Adverse Event Burden in Schizophrenia: Establishing Evidence-Based Practice

John W. Newcomer, Peter J. Weiden, and Robert W. Buchanan

Read this Academic Highlights to receive evidence-based guidance concerning when and how it is appropriate to undertake elective changes in antipsychotic medications in order to reduce adverse effects, particularly those associated with increased long-term health risks.

>>See the entire activity

>>See all available Academic Highlights

Measurement-Based Strategies to Assess and Manage Schizophrenia

Leslie Citrome, MD, MPH (Chair), et al

In this Supplement, discover how to distinguish between primary and secondary negative symptoms, find out how to assess treatment response and functioning, and review new therapeutic targets in the treatment of schizophrenia.

>>See the entire supplement

>>See all available supplements


rTMS for Treatment-Resistant Depression: A Review

Bradley N. Gaynes, MD (Chair), et al

If your patient's depression has not remitted after 2 adequate antidepressant trials, do you consider repetitive transcranial magnetic stimulation (rTMS)? Read this CME article for a review of rTMS in treatment-resistant depression.

>>See the entire activity

>>See all Journal CME activities

Current Standards of Treatment in MS and the Role of Oral Agents

Harold Moses, Jr, MD

New! In this Neurology Report, learn about the efficacy and safety profiles of current MS treatments. Plus, weigh the advantages and disadvantages associated with oral medications.

>>See the entire activity

>>See all Multimedia activities

Clinical and Cost Implications of Treating Schizophrenia

John M. Kane, MD (Chair), et al

Read this PEARL 3 InfoPack to explore strategies to enhance cognition in your patients with schizophrenia. Plus, learn about effects of short- and long-term antipsychotics and costs associated with treatment.

>>See the entire activity

>>See all Special Features

Learn. Practice. Treat.

Recognizing Negative Symptoms and Domains in Schizophrenia

Brian Kirkpatrick, MD, MSPH

Here, find out how to differentiate and treat the cause of negative symptoms and learn to recognize symptoms of apathy and diminished expression to comprehensively treat schizophrenia.

>>See the entire activity

>>See related activities

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Journal Statistics and Impact Information

Journal Statistics (2013 Data)

Acceptance rate



No. of articles published per issue



Submission-to–first decision time (mean)


47 days

Submission-to–final decision time (mean)


66 days

Submission-to-acceptance time (estimated average)


4.8 months

Acceptance-to-publication time


4.9 months

Impact Information

The Journal of Clinical Psychiatry continues to be ranked in the top ten of the most cited psychiatric journals in the world—and as the #1 clinical psychiatry journal—with an IF of 5.799. Moreover, the Journal is ranked as the world’s fourth most important psychiatric journal, with an Eigenfactor™ score of 0.03655 (December 2011, Journal Citation Reports). The Journal mails to about 34,690 recipients, and over 20,000 allied mental health professionals have requested daily receipt of informational e-mails about our journals and Web CME activities.

The Journal of Clinical Psychiatry is the official journal of the American Society of Clinical Psychopharmacology. The ASCP was founded in 1992, and its membership includes clinicians and researchers who study the use of pharmacology in clinical practice.

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The Journal of Clinical Psychiatry (JCP) offers authors of accepted articles and letters the opportunity to make their article freely available to nonsubscribers on JCP’s Web site, PSYCHIATRIST.COM. The charge for this service is $2,500 and is payable by check or credit card. Authors are provided this option at the time of acceptance.

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Manuscripts that meet the Journal’s scope and submission criteria are sent to expert consultants for peer review.

Conflict of Interest

Reviewers who have a financial or personal conflict of interest related to a manuscript are obligated to decline the reviewer position.

Processing of Peer Reviews

The peer review process is conducted using the electronic submission system used for manuscripts. Potential reviewers are queried in advance about their availability. While reviewers are asked to complete their reviews within 3 weeks of receiving the manuscript, more expeditious turnaround is highly valued. If you would like to be a peer reviewer, please send your CV to .


The reviewers' identities are not revealed, and strict confidentiality regarding the submitted manuscript is maintained. Reviewers must not keep copies of the manuscripts they review or discuss any of the information or data with others.

Circle of Honor

Peer review is essential to a medical journal, and each year, those peer reviewers who have carried the heaviest load and reviewed the greatest number of manuscripts are recognized as members of the Journal’s Circle of Honor.

The Circle of Honor is the Journal’s acknowledgment of the indispensable contribution—the dedication, scholarship, and scientific rigor—generously donated by these individuals.

2013 Circle of Honor

Chittaranjan Andrade, MD

Scott A. Freeman, MD

Jerry L. Halverson, MD

Ahmad Hameed, MD

James W. Jefferson, MD

James H. Kocsis, MD

Susan G. Kornstein, MD

Mario Maj, MD

John C. Markowitz, MD

Susan L. McElroy, MD

Roger E. Meyer, MD

J. Craig Nelson, MD

Michael K. Popkin, MD

Jerrold F. Rosenbaum, MD

Barbara O. Rothbaum, PhD

Erika F. H. Saunders, MD

Mauricio Tohen, MD, DrPH

Mark Zimmerman, MD

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