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Focus On Alzheimer’s Disease and Related Disorders

Eric M. Reiman, M.D., serves as deputy editor of this section, which encourages scientific studies of Alzheimer’s disease, promotes the optimal care of patients, and helps to keep the psychiatric community informed of the latest scientific and clinical developments. See our information on submitting a manuscript to this section.

2007 April

Entering the Era of High-Density Genome-Wide Association Studies

Eric M. Reiman

[PDF]

A High-Density Whole-Genome Association Study Reveals That APOE Is the Major Susceptibility Gene for Sporadic Late-Onset Alzheimer's Disease

Keith D. Coon, Amanda J. Myers, David W. Craig, Jennifer A. Webster, John V. Pearson, Diane Hu Lince, Victoria L. Zismann, Thomas G. Beach, Doris Leung, Leslie Bryden, Rebecca F. Halperin, Lauren Marlowe, Mona Kaleem, Douglas G. Walker, Rivka Ravid, Christopher B. Heward, Joseph Rogers, Andreas Papassotiropoulos, Eric M. Reiman, John Hardy, and Dietrich A. Stephan

[Abstract] [PDF]

2007 March

Clinical Trials and Tribulations

Eric M. Reiman

[PDF]

Study Design Factors and Patient Demographics and Their Effect on the Decline of Placebo-Treated Subjects in Randomized Clinical Trials in Alzheimer's Disease

Michael Gold

[Abstract] [PDF]

Antiaggressive Effect of Cyproterone Versus Haloperidol in Alzheimer's Disease: A Randomized Double-Blind Pilot Study

David Huertas, Juan J. López-Ibor Aliño, Juan D. Molina, Lorenzo Chamorro, Juana Balanza, María P. Jiménez, and Mercedes Hornillos

[Abstract] [PDF]

Helping Families With End-of-Life Care in Alzheimer's Disease

Paul Kettl

[Abstract] [PDF]

2006 December

The Non-Alzheimer Dementias

Eric M. Reiman

[PDF]

A Review of the Non-Alzheimer Dementias

Bradley F. Boeve

[Abstract] [PDF]

2006 November

A 100-Year Update on Alzheimer's Disease and Related Disorders

Eric M. Reiman

[PDF]

Alzheimer's Disease A Century Later

Richard J. Caselli, Thomas G. Beach, Roy Yaari, and Eric M. Reiman

[Abstract] [PDF]

2006 April

The Genetic, Transcriptomic, and Proteomic Study of Alzheimer's Disease

Eric M. Reiman

[PDF]

Genetics, Transcriptomics, and Proteomics of Alzheimer's Disease

Andreas Papassotiropoulos, Michael Fountoulakis, Travis Dunckley, Dietrich A. Stephan, and Eric M. Reiman

[Abstract] [PDF]

2005 July

Genetics, Cholesterol, and the Risk of Alzheimer's Disease

Eric M. Reiman

[PDF]

A Cluster of Cholesterol-Related Genes Confers Susceptibility for Alzheimer's Disease

Andreas Papassotiropoulos, M. Axel Wollmer, Magdalini Tsolaki, Fabienne Brunner, Dimitra Molyva, Dieter Lütjohann, Roger M. Nitsch, and Christoph Hock

[Abstract] [PDF]