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Early Career Psychiatrists

Marlene P. Freeman, M.D., serves as editor of this section, which represents work in the field by investigators beginning their career trajectories, launching this section and their careers with topics at the forefront of clinical psychiatric research. See our information on submitting a manuscript to this section.

2014 April

The Changing Landscape of Psychiatry.

Marlene P. Freeman

[Purchase] [Full Text]

Urinary Tract Infections in Acute Psychosis.

Krystle L. Graham, Chelsea M. Carson, Amaka Ezeoke, Peter F. Buckley, and Brian J. Miller

[Abstract] [Full Text]

Attention-Deficit/Hyperactivity Disorder Symptom Expression: A Comparison of Individual Age at Onset Using Item Response Theory.

Hugo Peyre, Nicolas Hoertel, Samuele Cortese, Eric Acquaviva, Pierre De Maricourt, Frédéric Limosin, and Richard Delorme

[Abstract] [Full Text]

The Mental Health Characteristics of Pregnant Women With Depressive Symptoms Identified by the Edinburgh Postnatal Depression Scale.

Linda B. Lydsdottir, Louise M. Howard, Halldora Olafsdottir, Marga Thome, Petur Tyrfingsson, and Jon F. Sigurdsson

[Abstract] [Full Text]

The Relationship Between Acculturation, Discrimination, and Suicidal Ideation and Attempts Among US Hispanics in the National Epidemiologic Survey of Alcohol and Related Conditions.

M. Mercedes Perez-Rodriguez, Enrique Baca-Garcia, Maria A. Oquendo, Shuai Wang, Melanie M. Wall, Shang-Min Liu, and Carlos Blanco

[Abstract] [Full Text]

The Relationship Between Affective State and the Rhythmicity of Activity in Bipolar Disorder.

Robert Gonzalez, Carol A. Tamminga, Mauricio Tohen, and Trisha Suppes

[Abstract] [Full Text]

The Relationship Between Bipolar Disorder and Biological Rhythms [REVIEW].

Robert Gonzalez

[Abstract] [Full Text]

2014 February

Response to Antidepressant Medications in Late-Life Depression Across the Spectrum of Cognitive Functioning.

Aaron M. Koenig, Meryl A. Butters, Amy Begley, Semhar Ogbagaber, Abdus S. Wahed, and Charles F. Reynolds III

[Abstract] [Full Text]

2013 November

Introduction: Early Career Offerings.

Marlene P. Freeman

[Purchase] [Full Text]

Probability and Predictors of First Treatment Contact for Anxiety Disorders in the United States: Analysis of Data From the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC).

Miren Iza, Mark Olfson, Donna Vermes, Marcela Hoffer, Shuai Wang, and Carlos Blanco

[Abstract] [Full Text]

Modafinil Augmentation Therapy in Unipolar and Bipolar Depression: A Systematic Review and Meta-Analysis of Randomized Controlled Trials [Meta-Analysis].

Alexander J. Goss, Muzaffer Kaser, Sergi G. Costafreda, Barbara J. Sahakian, and Cynthia H. Y. Fu

[Abstract] [Full Text]

Symptomatic Remission and Cognitive Impairment in First-Episode Schizophrenia: A Prospective 3-Year Follow-Up Study.

Wing Chung Chang, Christy Lai Ming Hui, Gloria Hoi Yan Wong, Sherry Kit Wa Chan, Edwin Ho Ming Lee, and Eric Yu Hai Chen

[Abstract] [Full Text]

2013 July

Lamotrigine in Psychiatric Disorders.

Jennifer G. Reid, Michael J. Gitlin, and Lori L. Altshuler

[Abstract] [Full Text]

2013 March

Commentary: Teaching the Teacher: A Report From the Third Annual American Society of Clinical Psychopharmacology Teaching Session.

Ira D. Glick, Sidney Zisook, and Mark H. Rapaport

[Purchase] [Full Text]

Generalizability of Clinical Trial Results for Bipolar Disorder to Community Samples: Findings From the National Epidemiologic Survey on Alcohol and Related Conditions.

Nicolas Hoertel, Yann Le Strat, Pierre Lavaud, Caroline Dubertret, and Frédéric Limosin

[Abstract] [Full Text]

A Prevalence Study of Urinary Tract Infections in Acute Relapse of Schizophrenia.

Brian J. Miller, Krystle L. Graham, Chelsea M. Bodenheimer, Nick H. Culpepper, Jennifer L. Waller, and Peter F. Buckley

[Abstract] [Full Text]

2012 August

Can Women Have It All? Psychiatry and the Gender Gap.

Marlene P. Freeman

[Purchase] [Full Text]

The Differential Roles of Trauma, Posttraumatic Stress Disorder, and Comorbid Depressive Disorders on Suicidal Ideation in the Elderly Population.

Heide Glaesmer and Elmar Braehler

[Abstract] [Full Text]

A Cross-Sectional Study of Plasma Risperidone Levels With Risperidone Long-Acting Injectable: Implications for Dopamine D2 Receptor Occupancy During Maintenance Treatment in Schizophrenia.

Saeko Ikai, Gary Remington, Takefumi Suzuki, Hiroyoshi Takeuchi, Takashi Tsuboi, Ryosuke Den, Jinichi Hirano, Kenichi Tsunoda, Masahiko Nishimoto, Koichiro Watanabe, Masaru Mimura, David Mamo, and Hiroyuki Uchida

[Abstract] [Full Text]

Does Varenicline Worsen Psychiatric Symptoms in Patients With Schizophrenia or Schizoaffective Disorder? A Review of Published Studies.

Joseph M. Cerimele and Alejandra Durango

[Abstract] [Full Text]

2012 April

New Clinical Drug Evaluation Unit (NCDEU) Annual Meeting: A Great Opportunity for Early Career Psychiatrists.

John M. Kane, Lauren D. Hill, Bruce J. Kinon, William Z. Potter, Mark H. Rapaport, and Nina R. Schooler

[Abstract] [Full Text]

The Psychiatric Manifestations of Mitochondrial Disorders: A Case and Review of the Literature.

Rebecca E. Anglin, Sarah L. Garside, Mark A. Tarnopolsky, Michael F. Mazurek, and Patricia I. Rosebush

[Abstract] [Full Text]

Race and Long-Acting Antipsychotic Prescription at a Community Mental Health Center: A Retrospective Chart Review.

Neil Krishan Aggarwal, Robert A. Rosenheck, Scott W. Woods, and Michael J. Sernyak

[Abstract] [Full Text]

Can People With Nonsevere Major Depression Benefit From Antidepressant Medication?

Jessica A. Stewart, Deborah A. Deliyannides, David J. Hellerstein, Patrick J. McGrath, and Jonathan W. Stewart

[Abstract] [Full Text]

Minimum Clinically Important Difference in the Positive and Negative Syndrome Scale With Data From the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE)

Eric D. A. Hermes, Daniel Sokoloff, T. Scott Stroup, and Robert A. Rosenheck

[Abstract] [Full Text]

d-Cycloserine Augmentation of Behavioral Therapy for the Treatment of Anxiety Disorders: A Meta-Analysis

Allyson Bontempo, Kaitlyn E. Panza, and Michael H. Bloch

[Abstract] [Full Text]

2011 December

Efficacy of Antidepressants for Late-Life Depression: A Meta-Analysis and Meta-Regression of Placebo-Controlled Randomized Trials.

Enrico Tedeschini, Yeciel Levkovitz, Nadia Iovieno, Victoria E. Ameral, J. Craig Nelson, and George I. Papakostas

[Abstract] [Full Text]

Association Between Patient Beliefs Regarding Assigned Treatment and Clinical Response: Reanalysis of Data From the Hypericum Depression Trial Study Group.

Justin A. Chen, George I. Papakostas, Soo Jeong Youn, Lee Baer, Alisabet J. Clain, Maurizio Fava, and David Mischoulon

[Abstract] [Full Text]

Stress and Inflammation Reduce Brain-Derived Neurotrophic Factor Expression in First-Episode Psychosis: A Pathway to Smaller Hippocampal Volume.

Valeria Mondelli, Annamaria Cattaneo, Martino Belvederi Murri, Marta Di Forti, Rowena Handley, Nilay Hepgul, Ana Miorelli, Serena Navari, Andrew S. Papadopoulos, Katherine J. Aitchison, Craig Morgan, Robin M. Murray, Paola Dazzan, and Carmine M. Pariante

[Abstract] [Full Text] [Supplementary Material]

Variants of the Serotonin Transporter Gene, Selective Serotonin Reuptake Inhibitors, and Bone Mineral Density in Risperidone-Treated Boys: A Reanalysis of Data From a Cross-Sectional Study With Emphasis on Pharmacogenetics.

Chadi A. Calarge, Vicki L. Ellingrod, Bridget Zimmerman, Michael M. Bliziotes, and Janet A. Schlechte

[Abstract] [Full Text]

Time to Treatment Response in First-Episode Schizophrenia: Should Acute Treatment Trials Last Several Months?.

Juan A. Gallego, Delbert G. Robinson, Serge M. Sevy, Barbara Napolitano, Joanne McCormack, Martin L. Lesser, and John M. Kane

[Abstract] [Full Text]

2011 August

Acupuncture for the Treatment of Major Depressive Disorder: A Randomized Controlled Trial.

Carmen Andreescu, Ronald M. Glick, Chetachi A. Emeremni, Patricia R. Houck, and Benoit H. Mulsant

[Abstract] [Full Text]

Measurement-Based Care in Psychiatric Practice: A Policy Framework for Implementation.

Kelli Jane K. Harding, A. John Rush, Melissa Arbuckle, Madhukar H. Trivedi, and Harold Alan Pincus

[Abstract] [Full Text]

Antidepressants for Major Depressive Disorder and Dysthymic Disorder in Patients With Comorbid Alcohol Use Disorders: A Meta-Analysis of Placebo-Controlled Randomized Trials.

Nadia Iovieno, Enrico Tedeschini, Kate H. Bentley, A. Eden Evins, and George I. Papakostas

[Abstract] [Full Text]

2011 January

Treating Nonspecific Anxiety and Anxiety Disorders in Patients With Bipolar Disorder: A Review.

Jeffrey J. Rakofsky and Boadie W. Dunlop

[Abstract] [Full Text]

Efficacy and Cognitive Side Effects of Electroconvulsive Therapy (ECT) in Depressed Elderly Inpatients With Coexisting Mild Cognitive Impairment or Dementia.

Lucrezia Hausner, Marinella Damian, Alexander Sartorius, and Lutz Frölich

[Abstract] [Full Text]

Placebo-Controlled, Antidepressant Clinical Trials Cannot Be Shortened to Less Than 4 Weeks’ Duration: A Pooled Analysis of Randomized Clinical Trials Employing a Diagnostic Odds Ratio–Based Approach.

Enrico Tedeschini, Maurizio Fava, and George I. Papakostas

[Abstract] [Full Text]

White Matter Hyperintensities, Medial Temporal Lobe Atrophy, Cortical Atrophy, and Response to Electroconvulsive Therapy in Severely Depressed Elderly Patients.

Mardien L. Oudega, Eric van Exel, Mike P. Wattjes, Hannie C. Comijs, Philip Scheltens, Frederik Barkhof, Piet Eikelenboom, Anton J. M. de Craen, Aartjan T. F. Beekman, and Max L. Stek

[Abstract] [Full Text]

2010 May

Commentary: Frequently Asked Questions About Maintenance of Certification (MOC).

Larry R. Faulkner and Patricia A. Vondrak

[Purchase] [Full Text]

Topiramate in the Treatment of Substance-Related Disorders: A Critical Review of the Literature.

Ann K. Shinn and Shelly F. Greenfield

[Abstract/Purchase] [Full Text]

2009 November

Early Career Psychiatry.

Marlene P. Freeman

[Purchase] [Full Text]

Delayed Posttraumatic Stress Disorder: Systematic Review, Meta-Analysis, and Meta–Regression Analysis of Prospective Studies.

Geert E. Smid, Trudy T. M. Mooren, Roos C. van der Mast, Berthold P. R. Gersons, and Rolf J. Kleber

[Abstract/Purchase] [Full Text]

Specific Features of Suicidal Behavior in Patients With Narcissistic Personality Disorder.

Hilario Blasco-Fontecilla, Enrique Baca-Garcia, Kanita Dervic, M. Mercedes Perez-Rodriguez, Jorge Lopez-Castroman, Jeronimo Saiz-Ruiz, and Maria A. Oquendo

[Abstract/Purchase] [Full Text]

Effects of Lithium on Cognitive Performance: A Meta-Analysis.

Aliza P. Wingo, Thomas S. Wingo, Philip D. Harvey, and Ross J. Baldessarini

[Abstract/Purchase] [Full Text]

Commentaries on Peer Review and the Evolving Journal

Marlene P. Freeman

[Purchase] [Full Text With Forum] [Forum]

Peer Review Perspective for Early Career Psychiatrists

Alan J. Gelenberg

[Purchase] [Full Text With Forum] [Forum]

Learning to Review

Robert Freedman

[Purchase] [Full Text With Forum] [Forum]

Peer Review by Early Career Psychiatrists: An Opportunity for Development

Anne F. Gross, Ilse R. Wiechers, and Theodore A. Stern

[Purchase] [Full Text With Forum] [Forum]

The Evolution of the Psychiatry Research Journal

John H. Krystal

[Purchase] [Full Text With Forum] [Forum]

Peer Review in Early Career: Just Say Yes!

Peter P. Roy-Byrne

[Purchase] [Full Text With Forum] [Forum]

2009 July

Location, Location, Location: The Role of Place in Career Development.

Marlene P. Freeman

[PDF]

Varenicline Augmentation in Depressed Smokers: An 8-Week, Open-Lable Study.

Noah S. Philip, Linda L. Carpenter, Audrey R. Tyrka, Laura B. Whiteley, and Lawrence H. Price

[Abstract] [PDF]

Correlates of Historical Suicide Attempt in Rapid-Cycling Bipolar Disorder: A Cross-Sectional Assessment.

Keming Gao, Bryan K. Tolliver, David E. Kemp, Stephen J. Ganocy, Sarah Bilali, Kathleen L. Brady, Robert L. Findling, and Joseph R. Calabrese

[Abstract] [PDF]

Are Weight Gain and Metabolic Side Effects of Atypical Antipsychotics Dose Dependent? A Literature Review.

Viktoria Simon, Ruud van Winkel, and Marc De Hert

[Abstract] [PDF]

Commentary: Three (Ancient) Questions for the Academic Psychiatrist .

Michael W. Kahn

[PDF]

2009 January

Introduction. This Month's ECP Selections.

Marlene P. Freeman

[PDF]

Editorial. e-Etiquette.

Alan J. Gelenberg

[PDF]

Modafinil as an Adjunctive Treatment of Sedation, Negative Symptoms, and Cognition in Schizophrenia: A Critical Review.

Carlos Saavedra-Velez, Anna Yusim, Deepti Anbarasan, and Jean-Pierre Lindenmayer

[Abstract] [PDF]

A 6-Month, Double-Blind, Maintenance Trial of Lithium Monotherapy Versus the Combination of Lithium and Divalproex for Rapid-Cycling Bipolar Disorder and Co-Occurring Substance Abuse or Dependence.

David E. Kemp, Keming Gao, Stephen J. Ganocy, Omar Elhaj, Sarah R. Bilali, Carla Conroy, Robert L. Findling, and Joseph R. Calabrese

[Abstract] [PDF]

Comparing Acute Toxicity of First- and Second-Generation Antipsychotic Drugs: A 10-Year, Retrospective Cohort Study.

Michael A. Ciranni, Thomas E. Kearney, and Kent R. Olson

[Abstract] [PDF]

ECP News. The New Investigator Program at the NCDEU Meeting: Opportunities Found for All.

Mark Hyman Rapaport

[PDF]

2008 November

Introduction. This Month's Selections.

Marlene P. Freeman

[PDF]

Commentary. Academic Psychiatry: The Effects of Gravity on Career Trajectory.

Marlene P. Freeman

[PDF]

Guest Editorial. Whither the Academic Psychiatrist?

Joseph F. Goldberg

[PDF]

Bipolar Disorder and Comorbid Personality Psychopathology: A Review of the Literature.

Alexander H. Fan and Joseph Hassell

[Abstract] [PDF]

Cross-Sectional Study on Prevalences of Psychiatric Disorders in Mutation Carriers of Huntington's Disease Compared With Mutation-Negative First-Degree Relatives.

Erik van Duijn, Elisabeth M. Kingma, Reinier Timman, Frans G. Zitman, Aad Tibben, Raymund A. C. Roos, and Rose C. van der Mast

[Abstract] [PDF]

Discontinuation of Maintenance Selective Serotonin Reuptake Inhibitor Monotherapy After 5 Years of Stable Response: A Naturalistic Study.

Tara M. Pundiak, Brady G. Case, Eric D. Peselow, and Loretta Mulcare

[Abstract] [PDF]

2008 August

Mentorship: The Genuine Article.

Marlene P. Freeman

[PDF]

The Impact of Mentorship.

Stefan Weinmann, Virginio Salvi, and Ruud van Winkel

[PDF]

Implementation of a Schizophrenia Practice Guideline: Clinical Results.

Stefan Weinmann, Susanne Hoerger, Monika Erath, Reinhold Kilian, Wolfgang Gaebel, and Thomas Becker

[Abstract] [PDF]

The Use of Antidepressants in Bipolar Disorder.

Virginio Salvi, Andrea Fagiolini, Holly A. Swartz, Giuseppe Maina, and Ellen Frank

[Abstract] [PDF]

Psychiatric Diagnosis as an Independent Risk Factor for Metabolic Disturbances: Results From a Comprehensive, Naturalistic Screening Program.

Ruud van Winkel, Jim van Os, Ivan Celic, Dominique Van Eyck, Martien Wampers, Andre Scheen, Joseph Peuskens, and Marc De Hert

[Abstract] [PDF]

2008 March

Clinical Trials and Tribulations: Perspectives on Research Career Development.

Marlene P. Freeman

[PDF]

Major Changes in Glucose Metabolism, Including New-Onset Diabetes, Within 3 Months After Initiation of or Switch to Atypical Antipsychotic Medication in Patients With Schizophrenia and Schizoaffective Disorder.

Ruud van Winkel, Marc De Hert, Martien Wampers, Dominique Van Eyck, Linda Hanssens, Andre Scheen, and Joseph Peuskens

[Abstract] [PDF]

A Randomized, Double-Blind, Placebo-Controlled Trial of Long-Acting Risperidone in Cocaine-Dependent Men

Tsafrir Loebl, Gustavo A. Angarita, Gladys N. Pachas, Kai-Lin Huang, Sang H. Lee, Johanna Nino, Tanya Logvinenko, Melissa A. Culhane, and A. Eden Evins

[Abstract] [PDF]

2007 November

Early Careers and New Data.

Marlene P. Freeman

[PDF]

A Systematic Review of Rates and Diagnostic Validity of Comorbid Adult Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder.

Aliza P. Wingo and S. Nassir Ghaemi

[Abstract] [PDF]

Comparison of Antidepressant Use Between Subjects With Bipolar Disorder and Major Depressive Disorder With or Without Comorbid Anxiety

Ayal Schaffer, John Cairney, Scott Veldhuizen, Amy Cheung, and Anthony Levitt

[Abstract] [PDF]

Effect of Olanzapine, Risperidone, and Haloperidol Treatment on Weight and Body Mass Index in First-Episode Schizophrenia Patients in India: A Randomized, Double-Blind, Controlled, Prospective Study.

Sahoo Saddichha, Narayana Manjunatha, Shahul Ameen, and Sayeed Akhtar

[Abstract] [PDF]