Brainstorms October 1, 2001

"Hit-and-Run" Actions at Dopamine Receptors, Part 2: Illustrating Fast Dissociation From Dopamine Receptors That Typifies Atypical Antipsychotics

J Clin Psychiatry 2001;62(10):747-748

Article Abstract
Brainstorms:

In last month’s BRAINSTORMS, we discussed a new hypothesis on the mechanism of action of atypical antipsychotics, namely the "hit-and-run" hypothesis.Here we illustrate this concept.