Suicidal Risk During Antidepressant Treatment
J Clin Psychiatry 2011;72(5):722 [letter]
© Copyright 2014 Physicians Postgraduate Press, Inc.
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Letter to the Editor
Because this piece does not have an abstract, we have provided for your benefit the first 3 sentences of the full text.
The recent report by Stübner and colleagues of a large clinical survey of over 142,000 European patients treated with various antidepressants from 1993–2008 concluded that antidepressant treatment may, rarely, increase risks of suicidal behavior. The rate of suicide was 3/142,090 in an unspecified exposure time, or 2.1/100,000, and for suicide attempts, 18/142,090, or 12.7/100,000.
The risk-ratio of 6.0 attempts/suicide in patients treated with antidepressants (presumably diagnosed with depressive or anxiety disorders) accords with comparable findings among patients with DSM-IV major depression under various conditions of treatment.