Antidepressant Use and Risk for Suicide Attempts in Bipolar Disorder
J Clin Psychiatry 2011;72(12):1697 [letter]
© Copyright 2014 Physicians Postgraduate Press, Inc.
Purchase This PDF for $40.00
If you are not a paid subscriber, you may purchase the PDF.
(You'll need the free Adobe Acrobat Reader.)
Receive immediate full-text access to JCP. You can subscribe to JCP online-only ($86) or print + online ($156 individual).
With your subscription, receive a free PDF collection of the NCDEU Festschrift articles. Hurry! This offer ends December 31, 2011.
If you are a paid subscriber to JCP and do not yet have a username and password, activate your subscription now.
As a paid subscriber who has activated your subscription, you have access to the HTML and PDF versions of this item.
Click here to login.
Did you forget your password?
Still can't log in? Contact the Circulation Department at 1-800-489-1001 x4 or send email
Letter to the Editor
Because this piece does not have an abstract, we have provided for your benefit the first 3 sentences of the full text.
The use of antidepressants in bipolar disorder remains controversial with respect to whether, and when, they may destabilize mood and worsen clinical course. Despite previously identified links between suicide attempts and the proportion of time spent with depression in bipolar disorder, few longitudinal studies have examined the relationship between antidepressant use and suicidal behavior specifically in bipolar disorder. Retrospective studies have reported a greater risk for suicide attempts among bipolar patients taking antidepressants alone than among those taking concomitant mood stabilizers or mood stabilizers alone, while prospective studies have found either no link between suicidal acts and antidepressant use or fewer suicide attempts when antidepressants are combined with mood stabilizers than during mood stabilizer therapy alone.