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Questions Raised by the Failure of a Trial of Short-Term Psychodynamic Therapy Versus Pharmacotherapy for Major Depressive Disorder

J Clin Psychiatry 2012;73(1):64-65

This commentary addresses questions raised by the failure of a clinical trial comparing short-term psychodynamic therapy with pharmacotherapy in the treatment of major depressive disorder. It addresses such issues as changes in how volunteers for clinical trials are recruited, publication bias, how gender and ethnicity can affect trial results.