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Editorial

6 Our Sincere Thanks

Alan J. Gelenberg and Marlene P. Freeman

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Commentary

27 The Current Crisis of Confidence in Antidepressants [CME]

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Original Articles

11 Cognitive Development in Adults With Attention-Deficit/Hyperactivity Disorder: A Controlled Study in Medication-Naive Adults Across the Adult Life Cycle

Joseph Biederman, Ronna Fried, Carter R. Petty, Janet Wozniak, Alysa E. Doyle, Aude Henin, Lyndsey Corkum, Kim Claudat, and Stephen V. Faraone

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17 Suicidality in Obsessive-Compulsive Disorder: Prevalence and Relation to Symptom Dimensions and Comorbid Conditions [CME]

Albina R. Torres, Ana Teresa A. Ramos-Cerqueira, Ygor A. Ferrão, Leonardo F. Fontenelle, Maria Conceição do Rosário, and Euripedes C. Miguel

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34 L-Theanine Relieves Positive, Activation, and Anxiety Symptoms in Patients With Schizophrenia and Schizoaffective Disorder: An 8-Week, Randomized, Double-Blind, Placebo-Controlled, 2-Center Study

Michael S. Ritsner, Chanoch Miodownik, Yael Ratner, Tatyana Shleifer, Maria Mar, Leonid Pintov, and Vladimir Lerner

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43 Health-Related Quality of Life Across the Anxiety Disorders: Results From the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC)

Jonathan S. Comer, Carlos Blanco, Deborah S. Hasin, Shang-Min Liu, Bridget F. Grant, J. Blake Turner, and Mark Olfson

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51 Cost-Effectiveness of Psychotherapy for Cluster C Personality Disorders: A Decision-Analytic Model in The Netherlands

Djøra I. Soeteman, Roel Verheul, Anke M. M. A. Meerman, Uli Ziegler, Bert V. Rossum, Jos Delimon, Piet Rijnierse, Moniek Thunnissen, Jan J. V. Busschbach, and Jane J. Kim

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60 Fluoxetine Treatment of Alcoholic Perpetrators of Domestic Violence: A 12-Week, Double-Blind, Randomized, Placebo-Controlled Intervention Study

David T. George, Monte J. Phillips, Mariel Lifshitz, Thomas A. Lionetti, David E. Spero, Niloofar Ghassemzedeh, Linda Doty, John C. Umhau, and Robert R. Rawlings

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66 Panic Attacks and Panic Disorder in a Population-Based Sample of Active Canadian Military Personnel [CME]

D. Jolene Kinley, John R. Walker, Corey S. Mackenzie, and Jitender Sareen

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75 Impact of Second-Generation Antipsychotics and Perphenazine on Depressive Symptoms in a Randomized Trial of Treatment for Chronic Schizophrenia

Donald E. Addington, Somaia Mohamed, Robert A. Rosenheck, Sonia M. Davis, Thomas Scott Stroup, Joseph P. McEvoy, Marvin S. Swartz, and Jeffrey A. Lieberman

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Early Career psychiatrists

81 Treating Nonspecific Anxiety and Anxiety Disorders in Patients With Bipolar Disorder: A Review

Jeffrey J. Rakofsky and Boadie W. Dunlop

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91 Efficacy and Cognitive Side Effects of Electroconvulsive Therapy (ECT) in Depressed Elderly Inpatients With Coexisting Mild Cognitive Impairment or Dementia

Lucrezia Hausner, Marinella Damian, Alexander Sartorius, and Lutz Frölich

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98 Placebo-Controlled, Antidepressant Clinical Trials Cannot Be Shortened to Less Than 4 Weeks’ Duration: A Pooled Analysis of Randomized Clinical Trials Employing a Diagnostic Odds Ratio–Based Approach

Enrico Tedeschini, Maurizio Fava, and George I. Papakostas

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104 White Matter Hyperintensities, Medial Temporal Lobe Atrophy, Cortical Atrophy, and Response to Electroconvulsive Therapy in Severely Depressed Elderly Patients

Mardien L. Oudega, Eric van Exel, Mike P. Wattjes, Hannie C. Comijs, Philip Scheltens, Frederik Barkhof, Piet Eikelenboom, Anton J. M. de Craen, Aartjan T. F. Beekman, and Max L. Stek

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Letters To the Editor

113 Schizophrenia-Related Outpatient Treatment of Medicaid-Financed Patients After Hospital Discharge

Maurits van den Noort and Peggy Bosch

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• Reply by Mark Olfson, Steven C. Marcus, and Jalpa A. Doshi

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114 Risks of Intermittent Antipsychotic Treatment in Schizophrenia

Takefumi Suzuki, Kensuke Nomura, and Koichiro Watanabe

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• Reply by Wolfgang Gaebel and Mathias Riesbeck

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115 Do Antidepressants Really Beget More Depressive Episodes?

Keith G. Rasmussen

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• Reply by S. Nassir Ghaemi

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Book Reviews

117 Windows to the Brain: Insights From Neuroimaging

Howard S. Kirshner

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117 Lishman’s Organic Psychiatry, 4th ed.

Ronald M. Salomon

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online CME Activities

These online CME activities are available for free to all our users. You must register to view them, even if you have institutional access.

e01 Addressing Adverse Effects of Antipsychotic Treatment in Young Patients With Schizophrenia

Christoph U. Correll

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e02 Strategies for Selecting Treatment and Mitigating Risk in Patients With Chronic Pain

Scott M. Fishman

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e03 Alternatives to Antidepressants in Treating Acute Bipolar Depression

Andrew A. Nierenberg

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e04 Pharmacotherapy for Late-Life Depression

George S. Alexopoulos

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information for authors

see www.psychiatrist.com/author.htm